Sartocon® Hydrosart® Cassette

Hydrosart® high performance membrane is a stabilized cellulose based membrane that has been optimized for biopharmaceutical process applications.

  • Hydrosart® is stable across a broad pH range.
  • Hydrosart® is extremely hydrophilic, making it non-protein binding, and virtually non-fouling.
  • Membrane cleaning, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations.

These features make Hydrosart® an ideal membrane for biological applications.

Item No.: 
3021446806E--SW
Availability: 
Piece
1

*Custom/bulk order quotes are provided within 72 hours of request.

Hydrosart® E-Screen ultrafiltration cassettes are available in the following nominal molecular weight cutoffs:

  • 2 kD
  • 5 kD
  • 10 kD
  • 30 kD
  • 100 kD
  • 300 kD

Hydrosart® 100 kD main applications are:

  • Virus purification
    • Viral vectors like AAV
    • Inactivated or attenuated viral vaccines: Polio, Dengue
    • Virus like particles
  • Removal of contaminants
  • Large mAb constructs

Applications

  • Industry
    Pharma / Biotech

Compliance Information

  • Bacterial Endotoxins
    < 0.18 EU/mL as determined by the LAL test
  • Biological Reactivity
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".

Dimensions

  • Filtration Area
    0.6 m²
  • Flow Channel Geometry
    Protein conc. >20% /or viscosity above.3cp

General Specifications

  • Cassette Format
    Sartocon Cassettes
  • Filter Format
    Cassettes

Materials of Construction

  • Integral Frame
    Polyvinylidene fluoride (PVDF)
  • Membrane Material
    Hydrosart®
  • Sealing Compound
    Silicone White (High chemical resistance)
  • Spacer
    Polypropylene (PP)

Operating Conditions

  • Maximum Inlet Pressure
    4 bar
  • pH Stability
    pH 2 – 14

Physicochemical Information

  • MWCO
    100 kDa
  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.

Product Information

  • Brand
    Sartocon®