Sartocube® Hydrosart® Cassette

Hydrosart® high performance membrane is a stabilized cellulose based membrane optimized for biopharmaceutical process applications. It is stable across a broad pH range and extremely hydrophilic, making it non-protein binding and virtually non-fouling.

  • Ultra-low protein adsorption
  • Easy cleaning
  • Higher yields
  • Long product life
  • Retains its performance even with repeated use without fouling or loss of retention

Item No.: 
3021443930E-BSW
Pieces
5

*Custom/bulk order quotes are provided within 72 hours of request.

Hydrosart® Ultrafiltration Cassettes are available in the following molecular weight cut offs:

2 kDa, 5kDa, 10 kDa, 30 kDa, 100 kDa, 300 kDa

Main applications are:

  • Oligonucleotide
  • Plasma protein processes
  • Coagulation factors (Factor VIII, Factor III)
  • Vaccines
  • Antibody Drug conjugates (ADC) processes - Peptide processes

Applications

  • Industry
    Pharma / Biotech

Compliance Information

  • Bacterial Endotoxins
    < 0.18 EU/mL as determined by the LAL test
  • Biological Reactivity
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".

Dimensions

  • Filtration Area
    3 m²
  • Flow Channel Geometry
    Protein conc. >20% /or viscosity above.3cp

General Specifications

  • Cassette Format
    Sartocube Cassettes
  • Filter Format
    Cassettes

Materials of Construction

  • Integral Frame
    Polyvinylidene fluoride (PVDF)
  • Membrane Material
    Hydrosart®
  • Sealing Compound
    Silicone White (High chemical resistance)
  • Spacer
    Polypropylene (PP)

Operating Conditions

  • Maximum Inlet Pressure
    4 bar
  • pH Stability
    pH 2 – 14

Physicochemical Information

  • MWCO
    10 kDa
  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.

Product Information

  • Brand
    Sartocube®
  • Sartoflow® 20, 1.4435, F/R38/P26, DIN

    The Sartoflow® 20 stainless steel holder with hydraulic is designed for TFF applications from 200 L to 2500 L volumes. The holder is optimized for use with 4 Sartocon® up to 20 Sartocube® production scale TFF cassettes (max. 14 m2). Typical applications of the Sartoflow® 20 system includes concentration and diafiltration of proteins, vaccines, antibodies, oligo nucleotides, endotoxin removal etc., cell harvesting and clarification processes.