Ambr® Crossflow

Tech Support Documents
Ambr® Crossflow Ambr® Crossflow Ambr® Crossflow Ambr® Crossflow
 

Study factors for manufacturability

Collect important information about the behaviour of the molecules in downstream processing already in an early stage

Automated, parallel trials

Up to 16 channels can be managed by one control station

Lowest process volumes

Small scale screening with 10 cm² membrane area | 5 mL recirculation volume

Flexibility of two different process scales

Mid-scale screening is also possible with Sartocon® Slice 50 which has 50 cm² membrane area

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Products (7)

  • Ambr® Crossflow System Package
    Ambr® Crossflow System Package
  • Ambr® Crossflow - 12 channel system (without control station)
    Ambr® Crossflow - 12 channel system (without control station)
    Item no.
    061-8A72
    Channels
    12
    Including Control Station
    8799107449440
  • Ambr® Crossflow - 4 channel system (without control station)
    Ambr® Crossflow - 4 channel system (without control station)
    Item no.
    061-8A70
    Channels
    4
    Including Control Station
    8799107449440
  • Ambr® Crossflow - 8 channel system (without control station)
    Ambr® Crossflow - 8 channel system (without control station)
    Item no.
    061-8A71
    Channels
    8
    Including Control Station
    8799107449440

    • Product Information
    ambr® crossflow
    The high throughput solution for parallel screening

    ambr® crossflow provides at early development stages access to molecule behavior related to viscosity, buffer composition, shear stress and performance in membrane processes. It enables a lot of important additional decision criteria for the final candidate selection and speeds up this process significantly.

    A small scale, high throughput automated system enables greater number of molecule | buffer combinations and process control conditions to be investigated. As a result early stage R&D productivity and efficiency will be improved significantly while costs per experiment are reduced.

    ambr® crossflow is a benchtop crossflow system optimised for ultrafiltration and diafiltration applications. It is a small scale screening system with a minimum recirculation volume of 5 mL and a dedicated new range of ambr® CF filter cassettes with 10 cm² membrane area. Parallel operation is achieved with 4 independent crossflow channels per module, with up to 4 modules managed by one control station. This means ambr® crossflow is capable of performing membrane screenings with up to 16 ambr® CF filters simultaneously.

    Intuitive hardware and software design ensures that the system is quick to set up and easy to use, while full system automation ensures reliable process control and reduced manual intervention.

    General Specifications

    • Pump Output
      0 – 50 mL/min

    Materials of Construction

    • Recirculation Vessel
      Polystyrene (PS)

    Operating Conditions

    • Maximum Operating Pressure
      3 bar (43.5 psi)
    • Minimum Operating Volume
      5 mL

    Product Information

    • Brand
      Ambr® crossflow

    Volume

    • Recirculation Vessel Volume
      120 mL
  • Ambr® CF Filter, Polyethersulfone 30 kD
    Ambr® CF Filter, Polyethersulfone 30 kD
    Item no.
    3MA1465910

    The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

  • Ambr® CF Filter Hydrosart®, 30 kD
    Ambr® CF Filter Hydrosart®, 30 kD
    Item no.
    3MA1445910

    The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® crossflow system.

  • Ambr® CF Filter, Polyethersulfone 100 kD
    Ambr® CF Filter, Polyethersulfone 100 kD
    Item no.
    3MA1466810

    The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

  • ambr® CF Filter Hydrosart® 10 kD
    ambr® CF Filter Hydrosart® 10 kD
    Item no.
    3MA1443910

    The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® crossflow system.

  • Ambr® CF Filter Hydrosart®, 5 kD
    Ambr® CF Filter Hydrosart®, 5 kD
    Item no.
    3MA1442910

    The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

  • Ambr® CF Filter, Polyethersulfone 5 kD
    Ambr® CF Filter, Polyethersulfone 5 kD
    Item no.
    3MA1462910

    The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

  • Ambr® CF Filter, Polyethersulfone 10 kD
    Ambr® CF Filter, Polyethersulfone 10 kD
    Item no.
    3MA1463910

    The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.

  • Ambr® CF Filter Hydrosart®, 100 kD
    Ambr® CF Filter Hydrosart®, 100 kD
    Item no.
    3MA1446810

    The Ambr® CF Filter is a ready to use, fully disposable 10 cm² crossflow ultrafilter that is designed for high throughput membrane screening and formulation development. The Ambr® CF Filter is available with two membrane materials and in a wide variety of MWCO’s. The Ambr® CF Filter is designed to be used with the Ambr® Crossflow system.