Octet® Anti-Mouse Fc Capture (AMC) Biosensors
Octet® Anti-Mouse Fc Capture (AMC) Biosensors are designed for kinetic characterization of interactions between mouse Fc-containing proteins and target analytes. Octet® AMC Biosensors are offered in a tray format. Each tray contains 96 biosensors. Larger orders include discounts. The 5-tray pack represents a 10% per tray discount; 20-tray case represents a 20% per tray discount.
Key Features of Octet® Anti-Mouse Fc Capture (AMC) Biosensors
- Capture-based immobilization of mouse Fc-containing proteins
- Designed for use in buffer or complex media
- Regenerable and cost-effective
Top Applications for Octet® Anti-Mouse Fc Capture (AMC) Biosensors
- Complete kinetic analysis (ka, kd, KD) between mouse Fc-containing proteins and target analytes
- Off-rate ranking of hybridoma and stable cell-line supernatants
- Epitope binning/mapping from crude or purified samples
Note: This product is not returnable. If you have any issues with this product, please contact your Sartorius sales representative for assistance.
- Item No.:
- 18-5088
- Availability:
- pcs
- Piece
- 1
*Custom/bulk order quotes are provided within 24 hours of request.
Choose your Octet® BLI Consumables
The Octet® Anti-Mouse Fc Capture (AMC) Biosensors are designed for kinetic characterization of interactions between mouse Fc-containing proteins and target analytes. Immobilization of mouse Fc-containing proteins onto the biosensor surface is achieved through a factory immobilized anti-mouse Fc-specific antibody, whose high-affinity for the mouse Fc domain provides a stable baseline required for demanding kinetics applications. It is recommended to use the AMC biosensors with IgG1, IgG2a and IgG2b subtypes; IgG3 should be evaluated on a case-by-case basis.
Streamlined Workflow
The Octet® AMC Biosensors on the Octet® platform allow to streamline high-throughput kinetic screening by enabling immobilization of human Fc-containing proteins onto the biosensors directly from crude or purified matrices, without the need for labor intensive purification or biotinylation steps.
Flexible Applications
The AMC biosensors provide a flexible platform for evaluating the kinetics between mouse Fc-containing proteins and their analytes. The main applications for AMC biosensors include: Complete kinetic analysis (kon, koff and KD) between mouse Fc-containing proteins and target analytes Off-rate ranking of hybridoma and stable cell-line supernatants Epitope binning/mapping from either crude or purified samples Tracking product integrity by measuring kon, koff and KD during upstream fermentation, downstream harvest and purification, post-derivatization (pegylation) and formulation development.
Cost-Effective Regeneration
The Octet® AMC Biosensors can be regenerated up to 10 times via a standard low-pH protocol in as little as 2 minutes, thus providing a cost-effective solution for analyzing a large number of samples or generating replicate data for ligand-analyte pairs.
Brochure
Datasheet
Technical Note
Applications
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ApplicationKinetics
Compliance Information
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GMP KitsNo
Features
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Device/Instrument Compatibility
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Octet® R8
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Octet® R4
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Octet® R2
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Octet® RH96
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Octet® RED96e
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Octet® RH16
- Octet® N1
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Octet® R8
Product Information
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BrandOctet®BLI
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Pack Size1
The Octet® AT is a tool for Octet® BLI biosensor transfer. Its ergonomic design delivers exceptional comfort and makes biosensor pickup and release quick and easy. The unique finger hook provides optimal balance and enhanced stability, contributing to reduced fatigue and increased productivity.
To be discontinued on July 26, 2023
384 well polypropylene microplate with black tilted bottom
Note: This product is not returnable. If you have any issues with this product, please contact your Sartorius sales representative for assistance.
384 well polypropylene microplate with black tilted bottom
Note: This product is not returnable. If you have any issues with this product, please contact your Sartorius sales representative for assistance.
Octet® Anti-Human Fc Capture (AHC) Biosensors are designed for kinetic characterization of interactions between human Fc-containing proteins and target analytes. Octet® AHC Biosensors are offered in a tray format. Each tray contains 96 biosensors. Larger orders include discounts. The 5-tray pack represents a 10% per tray discount; 20-tray case represents a 20% per tray discount.
Key Features of Octet® Anti-Human Fc
- Capture (AHC) Biosensors Capture-based immobilization of human Fc-containing proteins
- Regenerable and cost-effective
- Compatible with crude samples and complex media
Top Applications for Octet® Anti-Human Fc Capture (AHC) Biosensors
- Kinetic analysis of interactions between human Fc-containing proteins and target analytes
- Rapid epitope mapping/binning
Note: This product is not returnable. If you have any issues with this product, please contact your Sartorius sales representative for assistance.
Trays of 96 biosensors coated with goat-anti-mouse IgG. 5-tray pack represents a 10% per tray discount; 20-tray case represents a 20% per tray discount
Note: This product is not returnable. If you have any issues with this product, please contact your Sartorius sales representative for assistance.
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