Sartobran® P Cartridge 0.2µm 20 inch

Tech Support Documents
Sartobran® P Cartridge 0.2µm 20 inch
 

Sartobran® PSartobran® P with its unique low-binding cellulose acetate (CA) membrane is mainly used for the sterile filtration of blood & plasma products and vaccines. The ultra-low binding of the membrane material leads to highest product yield and exceptional filtration performance. Especially large, shear-stress sensitive proteins do not lose their structure and function when filtered through this special membrane. This will improve your product yield even further.

Item No.: 
5232507H2----IVG

*Custom/bulk order quotes are provided within 72 hours of request.

Choose your Sartobran® P

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Sterilizing-Grade, 0.2 µm Rated Filters
Sartobran® P Pore size: 0.45 | 0.2 µm (heterogeneous PES double layer)

Bioburden Reduction, 0.45 µm Rated Filters
Sartobran® P Pore size: 0.8 | 0.45 µm (heterogeneous PES double layer)

Your Benefits:

  • High product yield due to ultra-low unspecific adsorption
  • Excellent filtration results especially for large, shear-stress sensitive proteins
  • Exceptional total throughput especially for blood and plasma products
Sartobran® P filters are not suitable for gamma irradiation. Please check also Filter Transfer Sets for easy integration of non-gamma filters into single-use assemblies.
For highest process flexibility all Sartobran® P filters are available for conventional or single use applications. All filter elements are available in various sizes and adapter combinations. Please review the selection guide in the supporting resources literature.

Applications

  • Industry
    Pharma / Biotech

Biological Information

  • Bacterial Retention
    Quantitative Retention of 1 × E7 CFU/cm² Brevundimonas Diminuta ATCC® 19146 per ASTM methodology

Compliance Information

  • Bacterial Endotoxins
    < 0.18 EU/mL as determined by the LAL test
  • Biological Reactivity
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".

Dimensions

  • Filtration Area
    1.2 m²

General Specifications

  • Maximum Diffusion
    15 mL/min at 2.5 bar | 36 psi at 20 °C per 10 inch element
  • Minimum Required Bubble Point
    2.0 bar | 29 psi

Materials of Construction

  • Material o-ring | seal
    Silicone (optional EPDM or Fluoroelastomer)
  • Membrane Material
    Cellulose Acetate (CA)
  • Support Fleece
    Polypropylene (PP)

Operating Conditions

  • Maximum Differential Pressure
    20 °C: 5 bar, 80 °C: 2 bar

Physicochemical Information

  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.

Product Information

  • Brand
    Sartobran® P

Usage Protocols

  • Sterilization Procedures
    In-line steam sterilization: 134 °C, 20 min. at max. differential pressure of 0.5 bar.
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    Item no.
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