Top Features for Recombinant Human Fibroblast Growth Factor2:

  • Optimal use for expansion of MSCs and maintenance of undifferentiated PSCs
  • ADCF Level 1
  • High purity to ensure the safety of your process
  • Available in two different grades (Preclinical and GMP grade)

Preclinical grade:

  • Intended for preclinical ex vivo use
  • GMP transferable: Seamless transition from preclinical development to commercial manufacturing

GMP grade:

  • Intended for clinical ex vivo use
  • Endotoxin Level ≤ 50 EU/mg
  • Manufactured in accordance with applicable GMP guidelines
  • FDA Drug Master File (DMF) available
  • Technical and regulatory support available

Application
Item No.: 
1021-1000
Availability: 

*Custom/bulk order quotes are provided within 72 hours of request.

Letter of Authorization (LOA)

Place a request for a Letter of Authorization (LOA) for our Drug Master File (FDA)

CellGenix® rh Cytokines - Preclinical vs GMP

Both product grades are produced under the same conditions in a GMP facility, ensuring an equal product quality and performance. We offer a more comprehensive QC testing including tighter specifications and documentation for our GMP products: CellGenix® rh Cytokines - Preclinical vs GMP

CellGenix® Recombinant Human Fibroblast Growth Factor-2 (FGF-2) is an animal-derived component-free product. It is produced in a dedicated GMP facility. FGF-2 is used in the cell and gene therapy space for the expansion of bone marrow and adipose tissue derived mesenchymal stem cells (MSCs).

CellGenix® Recombinant Human FGF-2 is produced following all applicable GMP guidelines and allows for the safe use in accordance with USP Chapter <1043>, Ph. Eur. General Chapter 5.2.12 and ISO 20399:2022.

CellGenix® GMP cytokines are provided with documented evidence of purity, potency, consistency and stability. In combination with our expert regulatory and technical support this will help simplify your raw material qualification and validation efforts.

Expiry: ≥ 6 months from date of shipping

For the exact expiry date and the batch specific activity, please refer to the Certificate of Analysis on the My Sartorius Portal.

We have submitted Drug Master Files (DMFs) to US Health Authorities to support our customers’ regulatory activities. These Master Files can be cross-referenced through Letters of Authorization (LOAs) in Marketing Authorizations, IND, BLA, NDA, ANDA or other DMF applications. Please submit your Authorization Request via the form above.

icon-article

App Note:

Reliable T Cell Expansion with CellGenix®️ rh IL-2

Download Now
icon-article

App Note:

Performance of CellGenix® GMP TCM

Download Now
icon-article

Tech Note:

ADCF and Serum-free Policy

Download Now
icon-article

Tech Note:

Shipment at Ambient Temperatures

Download Now
icon-approval

Certificate of Analysis:

Download on the My Sartorius portal

My Sartorius
icon-article

Tech Note:

Stability of GMP Cytokines after Reconstitution 

Download Now
icon-article

Tech Note:

Batch-to-Batch Consistency of CellGenix® GMP Cytokines

Download Now

Applications

  • Application
    Clinical ex vivo use (large)
  • Application Area
    • Cell & gene therapy
    • Epithelial cell biology
    • Neuroscience
    • Stem cell biology
  • Cell Type
    • MSC
    • ESC/iPSC
    • Chondrocytes
    • Neuronal Cells
    • Organoids

Biological Information

  • Activity
    0.9 – 3 x 106 IU/mg

Compliance Information

  • GMP Compliance
    This product was manufactured in accordance with applicable Good Manufacturing Practice (GMP) guidelines.
  • Origin
    Animal-Component Free

Features

  • Carrier-Protein Free
    Yes

Physicochemical Information

  • Endotoxin
    ≤ 0.05 EU/µg
  • Expression System
    E. coli

Product Information

  • Brand
    CellGenix®
  • Package Type
    Vial
  • Size
    1 mg

Sterility/Purity

  • Delivery Condition
    Sterile
  • Purity
    ≥ 97%

Weight

  • Molecular Weight (kDa)
    17.3 kDa