HEA HyperCel - 1 L
HEA HyperCel is a mixed-mode resin with a less hydrophobic hexylamine ligand allowing protein binding at a moderate salt concentration under neutral pH.
- Price (USD):
- $4,900.00
- Item No.:
- 20250-041
- Piece
- 1
*Custom/bulk order quotes are provided within 72 hours of request.
Choose your HEA HyperCel
HEA HyperCel resin is an industry-scalable chromatography resin designed for protein capture and impurity removal in a biopharmaceutical environment. Operating on a “mixed-mode” mechanism, with a hexylamine ligand, its behavior is based on a combination of electrostatic and hydrophobic interactions of the proteins with the ligands. HEA HyperCel resin provides unique selectivities, different from those given by ion exchange or conventional HIC (hydrophobic interaction chromatography).
Features and Benefits
- High mechanical and chemical stability
- Suitable for large-scale chromatography in a biopharmaceutical environment
- Cross-linked cellulose base matrix
Applications
- Protein purification at low ionic strength by direct hydrophobic capture
- Separation of challenging mixtures, e.g. protein isoforms or proteins with very close pIs
- Orthogonal separation mechanism to ion exchange or HIC
Applications
-
ApplicationPreparative protein purification
Compliance Information
-
Quality Standards
-
CoA
- RSF
-
CoA
Dimensions
-
Bead Size80 - 100 µm
General Specifications
-
Flow Rate100-600cm/h
-
Resin FormatBulk resin
Materials of Construction
-
Base MatrixRigid cellulose beads
Operating Conditions
-
Operating Pressure< 3 barg (44psi)
-
pH Stability1 to 14 (short term), 2 to 12 (long term)
Physicochemical Information
-
LigandHexylamine
-
Reference ProteinBovine serum albumin (BSA)
-
Typical Dynamic Binding Capacity 10% per mL40-60 mg/mL BSA
Product Information
-
BrandHEA HyperCel
-
Pack Size1
-
Pack Volume1 L
-
Resin Delivery Condition1M NaCl with 20% EtOH
-
Resin TypeMixed-mode anion exchanger
-
What you receive1 bottle resin, instructions
Storage Conditions
-
Storage Conditions20% EtOH/1 M NaCl