iQue® Cell Membrane Integrity Dye (B/Red) Kit

Key Benefits

• Three dye options gives you more ways to measure cell death.
• No wash protocol, just add and read for fast, easily automated workflow.
• Multiplex with other IntelliCyt kits like Cell Cycle for richer content.

Principle

The Cell Membrane Integrity dyes are fluorescent molecules that are cell impermeant. Healthy cells with intact cell membranes will exclude the dyes. Unhealthy cells with compromised membranes will allow entry of the dye into the intracellular space. Upon entry to the cell, the dye localizes to the nucleus and binds to DNA by intercalation.

The whole family includes no-wash/1-wash protocols save time, increase productivity and allow for miniaturization. Reagents and kits can be multiplexed to increase assay content and reduce sample requirements.