Sartobind® Lab S Cation Exchange Membrane Adsorbers

Top Features of Sartobind® Lab S Cation Exchange Membrane Adsorbers

  • Rapid flow rates of 5 – 30 membrane volumes per minute
  • High dynamic binding capacity, especially for large proteins and viruses
  • Operate by syringe, peristaltic pump or FPLC system

Popular Applications for Sartobind® Lab S Cation Exchange Membrane Adsorbers

  • Protein and virus purification
  • Contaminant removal
  • Separation

Bed Volume
Price (USD):
$240.00
Item No.: 
93IEXS42DB-12--V
Availability: 

*Custom/bulk order quotes are provided within 24 hours of request.

Process-Ready Sartobind® Membrane Adsorbers

Sartobind® Lab membrane adsorbers for ion exchange chromatography are ready-to-use units in a syringe filter format. They are based on the patented macroporous Sartobind® membranes, with anion or cation exchange ligands covalently bound to the entire internal surface of the pores. This results in a chromatography matrix with superior flow rates and high binding capacity. Covalent linkage of ion exchange ligands to the membrane is very stable, allowing for many cycles of re-use without loss of binding capacity. In addition, these units utilize the same membrane adsorber platform as found in Sartobind® capsules and cassettes, making them ideal for research and development work, prior to convenient scale-up for manufacturing.

Ultimate Versatility

Sartobind® Lab units for ion exchange are available with strong or weak anion (Q and D) and strong cation (S) exchangers, and in three bed volumes, ranging from 0.41 to 2.8 mL, corresponding to dynamic binding capacities between 12 and 80 mg protein per unit. Equipped with standard Luer lock connectors, Sartobind® Lab units enable simple, equipment-free handling by syringe, or can be easily connected to FPLC systems for automated purifications. The units are compatible with most common chromatography buffers and can be re-used > 1,000 times, ensuring high-cost efficiency.

Applications

  • Application
    • Screening
    • Optimization
    • Purification
    • Separation
    • Polishing
    • Contaminants Removal

Connections (Physical)

  • Connector(s)
    Luer lock

Dimensions

  • Bed Height
    4 mm
  • Dimensions WxDxH
    36 x 28 mm
  • Membrane Area
    75 cm²

Features

  • Reusable
    Yes

Materials of Construction

  • Membrane Material
    Stabilized regenerated cellulose
  • Reinforcement Material
    Polyester

Operating Conditions

  • Maximum Operating Pressure
    0.6 MPa
  • Recommended Flow Rate
    10-63 mL/min (5-30 MV/min)
  • pH Stability
    pH 3 – 14 (short term), pH 4 – 13 (long term)

Physicochemical Information

  • Bed Volume
    2.1 mL
  • Chemical Compatibility
    Stable in common chromatography buffers, avoid peroxide and other oxidizing or reactive reagents
  • Ligand
    Sulfonic acid
  • Ligand Density
    2 – 5 µeq/cm²
  • Pore Size
    3 - 5 µm
  • Reference Protein
    Lysozyme
  • Typical Dynamic Binding Capacity 10% per unit
    52.5 mg
  • Void Volume
    1.7 mL

Product Information

  • Brand
    Sartobind® Lab
  • Membrane Type
    Strong cation exchanger
  • Pack Size
    2
  • Type
    Membrane adsorber
  • What you receive
    • 2 units
    • 1 operating instruction sheet

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