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- Chromatography
- Chromatography Consumables (Media)
- Chromatography Membranes
- Sartobind® S Nano
Sartobind® S Nano 1 mL with 4 mm bed height
Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.
- Item No.:
- 96IEXS42DN-11--A
- Availability:
- pcs
Sartobind® S membrane adsorber units combine the advantages of convective media and ion exchange chromatography for rapid and easy contaminant removal or capture of virus and virus like particles.
Overview
Specifications
Choose your Sartobind® S
Sartobind® S membrane adsorbers display a macro-porous structure with pore size of > 3 µm. Sulfonic acid ligands are bound covalently to the complete internal surface of the membrane, resulting in separation media of high binding capacity combined with exceptional high flow rates.
Applications:
The S membrane adsorber is successfully used in FDA-approved drug manufacture to remove host cell proteins at high flow rates. As a cation exchanger it displays not only aggregate removal capabilities but typically at least ten-fold higher binding capacity for viruses and virus-like-particles (VLP).
Benefits:
The Sartobind S adsorber speeds up the production process by high flow rate and opens new opportunities for the purification of therapeutic proteins and vaccines.
- High speed host cell protein removal up to 30 bed volumes/ min
- Aggregate removal
Easy to use:
- Plug and play devices from 0.08 ml to 5 l
- Can be used like a filter
- Flow rate up to 30 bed volumes/min
- Disposable or re-usable
Application Notes
Brochure
Datasheet
Flyer
User Manual
Applications
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ApplicationPolishing
Compliance Information
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Biological ReactivityAll materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
Connections (Physical)
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Connector(s)Female Luer lock
Dimensions
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Bed Height4 mm
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Dimensions37 x 31 mm
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Membrane Area36.4 cm²
Features
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ReusableYes
Materials of Construction
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Membrane MaterialStabilized reinforced cellulose
Operating Conditions
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Maximum Operating Pressure0.4 MPa
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Maximum Venting Pressure0.5 bar, 0.05 MPa, 7 psi
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Recommended Flow Rate20 mL/min
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pH StabilitypH 3 – 14 (short term), pH 4 – 13 (long term)
Physicochemical Information
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Bed Volume1 mL
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Chemical CompatibilityStable in common chromatography buffers, unstable to peroxide and other oxidizing or reactive reagents
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LigandSulfonic acid
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Ligand Density2 – 5 µeq/cm²
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Pore Size3 – 5 µm
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Reference ProteinLysozyme
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Thermal StabilitySartobind capsules with ion exchange membranes can be autoclaved at 121 °C for 30 min. We recommend one autoclaving cycle only.
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Typical Dynamic Binding Capacity 10% per unit25 mg
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Void Volume3.5 mL
Product Information
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BrandSartobind® S
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Membrane Adsorber FormatCapsules
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Membrane TypeStrong cation exchanger
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Pack Size4
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TypeMembrane adsorber
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What you receive
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4 capsules
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2 adapters Luer male to UNF 10-32 female
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1 operating instruction
- 1 certificate
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4 capsules