SART System™ Porticus

The SART System™ consists of an external port, an internal port, and a disposable connection device – the Gammasart ATD™.

The SART System™ and the Gammasart ATD™ connector have been extensively qualified for use in critical applications within biopharmaceutical manufacturing processes. The Gammasart ATD™ connectors are 100 percent air leak tested as a condition of lot release. In addition, the internal port of the SART System™ is tested at 350 mBars. A validation guide is available.

The SART System™ is based on a well-established alpha|beta concept to allow for reliable and secured fluid transfer while maintaining the integrity of the critical area–isolators, RABS, and cleanrooms. The SART System™ has been extensively qualified to ensure the robustness of the connection and grade-A environment continuity for aseptic processing. The Gammasart ATD™ connector design has been reviewed to improve the tightness of the connection, providing increased robustness of the assembly.

The disposable Gammasart ATD™ connector may be opened and re-used up to three times. Multiple transfers of different volumes can be processed without the need for re-sterilization. The disposable Gammasart ATD™ connector may be sterilized by autoclave or gamma irradiation, enabling use with either traditional vessels or fully disposable fluid-handling technologies.

The port is equipped with mechanical interlock systems that prevent an accidental opening without the Gammasart ATD™ connector in place and accidental release of the outer part of the connector. In the event of a stoppage on a filling line, the Gammasart ATD™ connector allows the bulk to be reliably removed from the line, stored, and reconnected later.