Sartobran® P Cartridge 0.45µm 10 inch

Tech Support Documents
Sartobran® P Cartridge 0.45µm 10 inch Sartobran® P Cartridge 0.45µm 10 inch
 

Sartobran® P with its unique low-binding cellulose acetate (CA) membrane is mainly used for the sterile filtration of blood & plasma products and vaccines. The ultra-low binding of the membrane material leads to highest product yield and exceptional filtration performance. Especially large, shear-stress sensitive proteins do not lose their structure and function when filtered through this special membrane. This will improve your product yield even further.

Item No.: 
5232506D1----P
Availability: 
Piece
1

*Custom/bulk order quotes are provided within 72 hours of request.

Choose your Sartobran® P

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Sterilizing-Grade, 0.2 µm Rated Filters
Sartobran® P Pore size: 0.45 | 0.2 µm (heterogeneous CA double layer)

Bioburden Reduction, 0.45 µm Rated Filters
Sartobran® P Pore size: 0.65 | 0.45 µm (heterogeneous CA double layer)

Your Benefits:

  • High product yield due to ultra-low unspecific adsorption
  • Excellent filtration results especially for large, shear-stress sensitive proteins
  • Exceptional total throughput especially for blood and plasma products

Sartobran® P filters are not suitable for gamma irradiation. Please check also Filter Transfer Sets for easy integration of non-gamma filters into single-use assemblies.
For highest process flexibility all Sartobran® P filters are available for conventional or single use applications. All filter elements are available in various sizes and adapter combinations. Please review the selection guide in the supporting resources literature.

User Manual

Directions for Use - Standard Filter Cartridges and Mini Cartridges
en 326.3 kB

Applications

  • Application
    • Blood and Plasma
    • Vaccine Production
  • Industry
    Pharma / Biotech

Compliance Information

  • Bacterial Endotoxins
    < 0.25 EU/mL as determined by the LAL test
  • Biological Reactivity
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".

Connections (Physical)

  • Connector Inlet
    2-Flange Bayonet Adapter with 226 Double O-ring (25)
  • Connector Outlet
    2-Flange Bayonet Adapter with 226 Double O-ring (25)

Dimensions

  • Filter Size
    10"(0.6 m² / 6.5 ft²)
  • Filtration Area
    0.6 m² / 6.5 ft²
  • Outer Diameter
    70 mm

General Specifications

  • Capsule/Cartridge Format
    Cartridges
  • Maximum Allowable Back Pressure
    2 bar (29 psi) at 20°C; 1 bar (14.5 psi) at 80°C
  • Maximum Diffusion
    15 mL/min at 1.5 bar | 22 psi
  • Minimum Required Bubble Point
    2.0 bar | 29 psi
  • Vent Valve
    N/A

Materials of Construction

  • Material o-ring | seal
    Silicone (SI)
  • Support Fleece
    Polypropylene (PP)

Operating Conditions

  • Maximum Differential Pressure
    20 °C: 5 bar, 80 °C: 2 bar

Physicochemical Information

  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.
  • Pore Size Final-filter
    0.45 µm
  • Pore Size Pre-filter
    0.65 µm

Product Information

  • Brand
    Sartobran®

Sterility/Purity

  • Sterilization Method
    Autoclavable & In-Line Steam Sterilizable

Usage Protocols

  • Sterilization Procedures
    • In-Line Steam Sterilization: at 134 °C, 20 min., 0.5 bar, min. 25 Cycles
    • Autoclaving: at 134°C, 30 min, 2 bar, min. 25 Cycles