Disposable capsules with ion exchange membranes for polishing in biomanufacturing.

Item No.: 
92MU0142DD-11
Availability: 

*Custom/bulk order quotes are provided within 72 hours of request.

Sartobind® capsules are especially suited for the removal of DNA, viruses and protein contaminants in biopharmaceutical production. Sartobind® membranes contain homogenously grafted binding sites on a reinforced cross-linked cellulose matrix. The large pores (>3 um) increase the process speed and avoid diffusion limits compared to conventional bead chromatography. Membrane adsorbers feature extremely short cycle times and provide exceptionally high flow rates and throughput. A large product portfolio of Sartobind® capsules help to introduce an economical solution to production without validation.

  • Simple handling
  • High speed polishing
  • Less buffer consumption
  • Disposable and ready-to-use

Applications

  • Application
    • Capturing
    • Polishing

Connections (Physical)

  • Connector(s)
    Female Luer lock

Dimensions

  • Bed Height
    4 mm
  • Dimensions WxDxH
    31 × 11 cm
  • Membrane Area
    2.9 cm²

Features

  • Reusable
    No

General Specifications

  • Filter Format
    Capsules
  • Flow Rate
    0.8 – 2.4 mL/min

Materials of Construction

  • Membrane
    • Strong anion exchanger
    • Strong cation exchanger
    • Salt tolerant anion exchanger
  • Membrane Material
    Stabilized reinforced cellulose

Operating Conditions

  • Maximum Operating Pressure
    0.6 MPa
  • Maximum Venting Pressure
    0.5 bar, 0.05 MPa, 7 psi
  • pH Stability
    Q, PA: 2 – 14 (short term), S: 3 – 14 (short term)

Physicochemical Information

  • Bed Volume
    0.08 mL
  • Ligand
    • Quaternary ammonium
    • Sulfonic acid
    • Primary amine (PA)
  • Ligand Density
    Q, S: 2 – 5 µeq/cm², PA: 18 – 22 µeq/cm²
  • Pore Size Final-filter
    3 – 5 µm
  • Reference Protein
    • Bovine serum albumin (BSA)
    • Lysozyme
  • Thermal Stability
    Sartobind capsules with ion exchange membranes can be autoclaved at 121 °C for 30 min. We recommend one autoclaving cycle only.
  • Void Volume
    0.4 mL

Product Information

  • Brand
    Sartobind® pico
  • Pack Size
    One each of Q, S and STIC PA
  • Type
    Membrane adsorber
  • What you receive
    • One each of Q
    • S and STIC PA
    • 1 operating instruction