Sartocon Slice 50, Hydrosart®

Tech Support Documents
Sartocon Slice 50, Hydrosart®
 

The Sartocon® Slice 50 is a ready to use 50 cm2 fully disposable crossflow module that is ideally suited for membrane screening and process development, available in a wide variety of MWCO’s and polymers. The Sartocon® Slice 50 can easily be used with the SARTOFLOW® Smart system as well as many other laboratory scale crossflow systems.

Item No.: 
3D91443950ELLPU
Availability: 
Piece
1

*Custom/bulk order quotes are provided within 72 hours of request.

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Hydrosart® high performance membrane is a stabilized cellulose based membrane that has been optimized for biopharmaceutical process applications. Hydrosart® is stable across a broad pH range, is extremely hydrophilic, making it non-protein binding, and virtually non-fouling. Membrane cleaning, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures and concentrations. These features make Hydrosart® an ideal membrane for biological applications.

Hydrosart® E-Screen ultrafiltration cassettes are available in the following nominal molecular weight cutoffs:

  • 2 kD
  • 5 kD
  • 10 kD
  • 30 kD
  • 100 kD
  • 300 kD

Hydrosart® 10 kD main applications are:

  • Removal of contaminants
  • Proteins
    • Albumin
    • Hemoglobin
  • ADC
  • Recombinant proteins
  • Antibody fragment bio-conjugates
  • Special mAb’s e.g. one heavy chain and 2 light chain mAb

Applications

  • Industry
    Pharma / Biotech

Compliance Information

  • Biological Reactivity
    All materials of this filter element meet the requirements of the current USP Biological Reactivity tests <88> for plastics Class VI (Systemic Injection, Intracutaneous and Implantation tests).
  • Extractables
    The total amount of extractables is well below the limits established by the current USP unter "Sterile Water for Injection".

Dimensions

  • Filtration Area
    50 cm²
  • Flow Channel Geometry
    Protein conc. >20% /or viscosity above.3cp

General Specifications

  • Cassette Format
    Slice 50 Cassettes
  • Filter Format
    Cassettes

Materials of Construction

  • Integral Frame
    Polypropylene (PP)
  • Membrane Material
    Hydrosart®
  • Sealing Compound
    Not Applicable
  • Spacer
    Polypropylene (PP)

Operating Conditions

  • Maximum Inlet Pressure
    3 bar
  • pH Stability
    pH 2 – 14

Physicochemical Information

  • MWCO
    10 kD
  • Non-Fiber Releasing
    This filter product complies with the title 21 of the Code of Federal Regulations (CFR), section 210.3(b)(6) and 211.72.

Product Information

  • Brand
    Sartocon®