Sartoflow® Advanced

Tech Support Documents
Sartoflow® Advanced
 

Full Flexibility Meets Outstanding TFF Performance

Flexible solution

01. - 2.1 m² membrane sizes | 10 L stainless steel vessel or 5, 10, 20 L single-use bags for recirculation

High product yields

4-piston membrane pump for low shear

Highly automated

Two pumps for feed and buffer addition, as well as full TMP control

Item No.: 
SFADVANCED
Piece
1

*Custom/bulk order quotes are provided within 72 hours of request.

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Sartoflow® Advanced is suitable for flexible use in laboratory environments, for process development and clinical trials as well as for small-scale production batches. Several standardized options are available that can be upgraded with additional options if requirements change during process development or production.

This TFF system is equipped with the established DCU-4 control unit that readily communicates with BioPAT® MFCS software.

The System can be configured to accept either Sartocon® Slice or full-sized Sartocon® cassettes, providing an exceptionally wide range of membrane surface areas. Since all Sartocon® TFF cassettes have the same hydrodynamic flow path length, the Sartoflow® Advanced can be linearly scaled up from 0.1 to 2.1 m² of membrane area. Its unique compact design has an ultra-low loop volume of ~200 mL, making it possible to concentrate even small process batches.

Applications

  • Application
    Purification of mAbs, ADC, vaccines, viral vectors, and recombinant proteins

Dimensions

  • Dimensions WxDxH
    1,100 × 800 × 680 mm
  • Membrane Area
    0.1 - 0.5 m² (optionally 0.7 - 2.1 m²)
  • Tube Size (ID – OD)
    1/2"

Features

  • Display
    Yes

General Specifications

  • Cassette Format
    • Sartocon Cassettes
    • Slice Cassettes
    • Standard Cassettes
  • Pump Output
    700 L/h @ 4 bar (60 psi)
  • Surface Roughness of Wetted Parts
    Ra <= 0.6 µm

Materials of Construction

  • Recirculation Vessel
    Stainless steel 316 L

Operating Conditions

  • Maximum Operating Pressure
    4 bar (58 psi)
  • Minimum Operating Volume
    ~200 mL

Power Requirements

  • Power Requirements
    230 VAC | 50 Hz 2.5 Amp; 120 VAC | 60 Hz 4 Amp

Product Information

  • Brand
    Sartoflow®

Volume

  • Recirculation Vessel Volume
    10 L (MU)
  • Volume
    Bag: 5, 10, 20 L (SU)

Weight

  • Total Weight
    ~ 120 kg
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    • Ultra-low protein adsorption
    • Easy cleaning
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    • Long product life
    • Retains its performance even with repeated use without fouling or loss of retention

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    • Ultra-low protein adsorption
    • Easy cleaning
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    • Stable polymer featuring a broad pH and temperature range

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    • Stable polymer featuring a broad pH and temperature range

    • Minimal adsorption of proteins, viruses, etc.
    • Membrane regeneration, storage and depyrogenation can be accomplished by using NaOH even at elevated temperatures
    • Membrane retention is unaffected by repeated re-use